Endocrine Abstracts

Background: Systematic or randomised studies on the natural course of non-functioning pituitary macroadenomas after surgery (NFPA) are lacking.Objectives: This study aimed to evaluate the long-term outcomes of residual NFPA following pituitary surgery.Methods: In this retrospective study, we included 130 patients with NPFA who underwent pituitary surgery between 2005 and 2018 at University Hospital Centre Zagreb. The median age of ...

Background: Cystic fibrosis (CF) is a genetic disorder in which a dysfunctional cystic fibrosis transmembrane regulator (CFTR) chloride channel can result in multimorbidity, including severe respiratory disease and reduced pancreatic exocrine secretion and diabetes. Recently, CFTR modulator therapy, has emerged with the potential of improving respiratory function and remission of diabetes. The effect of CFTR modulator therapy on pancreatic function in patients without preexist...

Corticotrope cells give arise to utmost aggressive and to very rare pituitary neoplasias, including pituitary carcinomas, Crooke’s cell adenomas (CCA), clinically non-functioning silent corticotrope adenomas (SCA) and the Cushing-provoking pituitary adenomas (CD). The molecular etiopathogenesis of these tumors are still poorly understood. Therefore, we carried out whole exome sequencing to better understand the full genomic landscape single nucleotide variants and copy nu...

Introduction: Prolonged QTc interval is a known risk factor for developing ventricular tachyarrhythmias. QTc prolongation is often reported in patients with pheochromocytoma, however the literature data on this issue are rather heterogeneous. Here we report the results of QTc measurement in patients with pheochromocytoma and paraganglioma (PPGL) in comparison to hormonally inactive benign adrenal tumors.Methods: The test group included 204 patients with ...

Background: Gestational diabetes mellitus (GDM) is common complication in pregnancy. During pandemic COVID-19, endocrine service iniciate telemedicine in medical care and monitoring blood glucose.Purpose: The purpose of this study was to asses metabolic control and pregnancy outcome during pregnancy in telematic consult.Materials and Methods: Descriptive study of 20 patients were assesed in telematic review in the first wave of the...

In 2000 female, 28 y.o., admitted endocrinologist with headache, high blood pressure, dark skin and muscle weakness. Lab data showed high levels of ACTH and cortisol, low potassium level. According to MRI scans, pituitary gland seemed normal. On CT in right adrenal was found 32 mm mass with the native density of 20 HU. Diagnosed ACTH-dependent Cushing syndrome (CS). As Mitotane was not available in Russia at that time, she received ketokonazole due to progression of CS but it ...

Background: A parathyroidectomy (PTX) is the preferred standard treatment for patients with primary hyperparathyroidism (PHPT). the assessment of the surgery success from patient’s perspective is important to provide patient-centered care.Aim: We aimed to evaluate QoL changes in PHPT patients during 2-years follow-up after PTX and to identify preoperative predictors of meaningful QoL improvement after surgery.Materials and Met...

Introduction: Strokes are common diabetes macrovascular complications. A good control of cardiovascular risk factors such as glycemic control has been proven to reduce the risk of its appearance. Aim: Describe diabetes prevalence in patients admitted to hospital because of a stroke, as well as their treatment and metabolic control.Patients and methods: Observational retrospective study of patients admitted to the Neurology section because of a s...

Aim: Evaluate results of bariatric surgery by using the Bariatric analysis and reporting outcome system (BAROS) scoring systemPatients and methods: Observational clinical study of consecutive cases of patients undergoing bariatric surgery in Reina Sofia University Hospital (Córdoba, Spain) and clinical follow-up in the Endocrinology service between January and December 2018. Statistical analysis performed with SPSS 24th version.<p class="abstext...

Introduction: Flash glucose monitoring (FGM) allows non-invasive glucose level assessment. Studies have shown that patients using FGM test their glucose levels more often than those who use traditional blood glucose testing. Given that a higher rate of glucose testing has showed to improve glycemic control our objective was to describe the change in the glycemic control and time in euglycemic range in patients with FGM and the effect of the number of scans in this control....